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KMID : 1231220210120010024
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Journal of the Korean Society for Research on Nicotine and Tobacco
2021 Volume.12 No. 1 p.24 ~ p.33
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Pilot Study on the Determination of Volatile Organic Compounds (VOCs) in Exhaled Breath of Each Cigarette Type
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Cho Young-Hwan
Kim Hyoung-Yong
Lee Jeom-Kyu
Kim Seung-Hyun
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Abstract
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Background: Since the indoor environments where most modern people live have little space, there is a possibility of exposure to harmful components of smokers’ breaths. Thus, it is necessary to investigate the volatile organic compounds (VOCs) that can affect secondhand smoking by analyzing the components of exhaled smoke.
Methods: From August 2019 to March 2020, 30 smokers and 10 nonsmokers were recruited in the Osong Life Science Complex. For exhaled breath collection, a tedlar bag (1 L) for breath-gas analysis was used. Carbon monoxide (CO) was measured during the collection, and VOCs were analyzed by thermal desorption-gas chromatography/mass spectrometry after pretreatment.
Results: According to exhaled breath analysis, pyridine, 2-methylfuran, and benzene were detected at a high frequency only in smokers, whereas 2-methylfuran and pyridine were detected in all cigarette and heated tobacco product (HTP) users. The amounts of 2-methylfuran, benzene, isoprene, pyridine, toluene, and pyrrole in exhaled breaths after smoking were significantly greater than in those before smoking. Based on the measured CO, it was difficult to distinguish nonsmokers, HTP users, and electronic cigarette users.
Conclusion: These results demonstrated that 2-methylfuran and pyridine can possibly be used as indicators of smoking status. In addition, secondhand smoking can potentially be evaluated by detecting the VOCs in the exhaled breaths of HTP users. However, further studies on these compounds are warranted to confirm this possibility.
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KEYWORD
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Indoor air quality, Secondhand smoking, Tobacco product, Exhalations, Volatile organic compounds
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